Amanda Spurdle is an NHMRC Senior Research Fellow and head of the Molecular Cancer Epidemiology Laboratory at the QIMR Berghofer Medical Research Institute. She began working in the field of molecular epidemiology of cancer at QIMR Berghofer in Brisbane in 2007. Her research currently encompasses studies of breast, colorectal, prostate and endometrial cancer. Major research efforts include the clinical classification of sequence variants in high-risk “familial” cancer genes, and large-scale international collaborative efforts to identify common genetic variants associated with predisposition to and prognosis of cancers. She leads the ENIGMA consortium developing and applying methods to classify variants in BRCA1, BRCA2 and other breast cancer genes.